Special hotkey combinations switch the mouse pointer between monitors instantly.
In addition, there is a feature called Ignore Deactivation, specially developed for gamers. The Multi-monitor Mouse feature provides additional abilities for using a mouse in work and games on a multi-monitor system, such as quick switching of the mouse pointer between monitors via hotkeys, the ability to lock the mouse pointer within its current monitor or application window, or wrapping the desktop.
Multi-Monitor Mouse for Work and Playing Games